TMG Trimethylglycine 750 mg — Methylation & Cardiovascular Support (100 Vcaps)
TMG (Trimethylglycine) 750 mg is a powerful methylation donor that assists in converting homocysteine to methionine — a critical step in preventing elevated homocysteine levels associated with cardiovascular disease.* TMG also acts as an osmoprotectant (protecting cells from osmotic stress) and supports liver function, athletic performance, and cognitive health.*
Key Benefits
Reduces elevated homocysteine — a key risk factor for heart disease and stroke*
Supports methylation pathways alongside B12, folate, and B6*
Acts as a cell-protective osmoprotectant — shields cells from osmotic stress*
Produces DMG (dimethylglycine) as a metabolic byproduct — supporting energy*
Supports liver fat metabolism and detoxification*
Who Is This For?
TMG is essential for individuals with MTHFR gene variants, elevated homocysteine levels, cardiovascular disease risk, those on high-protein diets, and anyone seeking to optimize their methylation cycle. Michelle Tonkin ND recommends TMG as part of comprehensive cardiovascular and methylation support protocols.
Frequently Asked Questions
Q: What's the difference between TMG and SAMe?
A: Both support methylation but through different pathways. TMG is more affordable and directly reduces homocysteine, while SAMe is a methylation end-product with additional mood benefits. They can be used complementarily.
Q: Does TMG help with fatty liver?
A: Yes — TMG supports choline and methionine metabolism, which are critical for liver fat processing. It's frequently used in fatty liver protocols.*
Q: Should I take TMG with methylfolate and B12?
A: Yes — TMG works synergistically with active B vitamins for optimal homocysteine reduction and methylation cycle support.