Calcium D-Glucarate 500 mg — Detoxification & Hormonal Balance (90 Caps)
Calcium D-Glucarate 500 mg provides D-glucaric acid bound to calcium — a powerful supplement for supporting the body's Phase II liver detoxification pathway (glucuronidation) and clearing excess estrogen and environmental toxins.* It works by inhibiting beta-glucuronidase, an enzyme that can deconjugate and recirculate toxins and steroid hormones before they're excreted.*
Key Benefits
- Supports glucuronidation — a critical liver detox pathway for estrogen and toxin clearance*
- Inhibits beta-glucuronidase to prevent reabsorption of conjugated estrogens*
- Supports hormonal balance — beneficial for estrogen dominance, PMS, and perimenopause*
- Promotes clearance of environmental toxins, carcinogens, and steroid hormones*
- Supports healthy breast, prostate, and colon tissue through toxin elimination*
Who Is This For?
Calcium D-Glucarate is highly recommended for women with estrogen dominance, fibrocystic breasts, endometriosis, uterine fibroids, or those in perimenopause. It's also valuable for individuals with high toxic exposures or those undergoing comprehensive detox protocols. Curated by Michelle Tonkin ND as part of hormonal health programs.
Frequently Asked Questions
Q: How does Calcium D-Glucarate support hormonal balance?
A: Estrogen is conjugated by the liver for excretion, but beta-glucuronidase can deconjugate it in the gut, allowing reabsorption. Calcium D-Glucarate inhibits this enzyme, ensuring estrogen is fully excreted.*
Q: Is this safe for men?
A: Yes — men benefit from toxin clearance and healthy estrogen metabolism. It's particularly useful for men with high estrogen levels or on aromatase-related concerns.
Q: Can I take this with DIM or Indole-3-Carbinol?
A: Yes — these are frequently combined for comprehensive estrogen detoxification support. Consult your practitioner for a personalized protocol.

